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Methods For Reducing the Symptoms of Autoimmunity and Inflammation Using Binding Proteins Against Antigens Exposed on Dead or Dying Cells
Methods For Reducing the Symptoms of Autoimmunity and Inflammation Using Binding Proteins Against Antigens Exposed on Dead or Dying Cells
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机译:使用针对暴露在死细胞或垂死细胞上的抗原的结合蛋白减少自身免疫和炎症症状的方法
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摘要
The present invention relates to a method for inhibiting a disease response in a subject comprising contacting dead or dying cells exposing an antigen selected from the group consisting of a phosphorylcholine (PC) determinant, a phosphatidyl serine (PS) determinant, a MDA determinant, and cardiolipin in the subject, with an antibody or recombinant protein that recognizes and binds the antigen that is exposed on the dead or dying cells, thereby inhibiting the pathologic response in the subject.
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