首页> 外国专利> 14400, 2838, 14618, 15334, 14274, 32164, 39404, 38911, 26904, 31237, 18057, 16405, 32705, 23224, 27423, 32700, 32712 and 12216, novel seven-transmembrane proteins/G-protein coupled receptors

14400, 2838, 14618, 15334, 14274, 32164, 39404, 38911, 26904, 31237, 18057, 16405, 32705, 23224, 27423, 32700, 32712 and 12216, novel seven-transmembrane proteins/G-protein coupled receptors

机译:14400、2838、14618、15334、14274、32164、39404、38911、26904、31237、18057、16405、32705、23224、27423、32700、32712和12216是新型七跨膜蛋白/ G蛋白偶联受体

摘要

The present invention relates to a newly identified receptor belonging to the superfamily of G-protein-coupled receptors. The invention also relates to polynucleotides encoding the receptor. The invention further relates to methods using the receptor polypeptides and polynucleotides as a target for diagnosis and treatment in receptor-mediated disorders. The invention further relates to drug-screening methods using the receptor polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the receptor polypeptides and polynucleotides. The invention further relates to procedures for producing the receptor polypeptides and polynucleotides.
机译:本发明涉及一种新鉴定的受体,该受体属于G蛋白偶联受体的超家族。本发明还涉及编码受体的多核苷酸。本发明进一步涉及使用受体多肽和多核苷酸作为在受体介导的疾病中进行诊断和治疗的靶标的方法。本发明还涉及使用受体多肽和多核苷酸鉴定激动剂和拮抗剂以进行诊断和治疗的药物筛选方法。本发明进一步包括基于受体多肽和多核苷酸的激动剂和拮抗剂。本发明进一步涉及产生受体多肽和多核苷酸的方法。

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