Substituted quinolines for the treatment of protozoa and retrovirus co-infections

摘要

The invention relates to the use of quinolines having general formula (I), wherein R₁ denotes H; alkyl C₁-C₁₅; alkenyl or alkynyl C₂-C₁₅; —CHO; heteroaryl; alkyl C₁-C₁₅ or alkenyl or alkynyl C₂-C₇ comprising at least one substituent selected from among O, halogen, —OH, —CHO, —COOH, aryloxycarbonyl, alkyloxycarbonyl C₂-C₈, alkenyloxycarbonyl C₃-C₉, nitrile, aryl, heteroaryl, arylsulphone, alkylsulphone C₁-C₇, thioalkyl or aminoalkyl C₁-C₇; alkenyl C₂-C ₇ bearing at least one substituent selected from among NH₂, aleoxy C₁-C₇, phenoxy, cycloakyl C₃-C₆ or heteroaryloxy, alkenyl or alkynyl C₂-C₁₅ comprising at least one trialkylsilyl C₁-C₇; R₂, in position 3, 6 or 8, denotes H; halogen; —OH; —CHO; —COOH; alkyl or aleoxy C₁-C₇; —NH2; alkenyl C₂-C₇; or alkynyl C₂-C₁₀; R₁ and R₂ do not both denote H. The invention is used for the preparation of a medicine to treat protozoan and retrovirus co-infections;