Sevoflurane anaesthetic compositions, method for its preparation, Methods for inhibiting their degradation in the presence of a Lewis acid and a process for preparing a stable anaesthetic composition in a Sealed container

摘要

An anesthetic composition comprising a fluoroether compound having an alpha fluoroether portion to which an effective stabilizing amount of a Lewis acid inhibitor except water was added; a method for its preparation, a method for stabilizing an anhydrous fluorether compound having an alpha fluorether portion, the method comprises the step of adding to the anhydrous fluorether compound, an effective stabilizing amount of a Lewis acid inhibitor except water to compound to prevent degradation of the fluoroether compound by Lewis acid,The invention relates to a method for inhibiting the degradation of Lewis acid and a process for manufacturing stable anesthetics in a sealed container, which is characterized in that: (a) providing a container; (b) adding Lewis acid inhibitors other than water to the container; (c) Seven flutamide were added to the containers obtained at level (b);(d) Seal the container.