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A cyanohydrin Synthesis of an Alpha Amino Acid from a cyanohydrin of an Alpha Amino Acid, continuously and without isolation of Intermediates
A cyanohydrin Synthesis of an Alpha Amino Acid from a cyanohydrin of an Alpha Amino Acid, continuously and without isolation of Intermediates
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机译:连续且无分离中间体的情况下,由α-氨基酸的氰醇合成氰醇
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摘要
This relates to a process for the continuous preparation of a - amino acid of the General formula (1) on the basis of which leads to a corresponding amino acid of the General formula (2) where R and R ', which can be identical or different, are optionally a ring, Represent each.H, alkyl, haloalquilo or heteroaryl containing between 1 and 30 C ATOMS, in a linear chain or branched; alquenilo or alquinilo containing between 2 and 30 C ATOMS, in a linear chain or branched; one or more cicloalquenilo or cycloalkyl groups, containing between 3 and cicloalquinilo 30 C Atoms.In a linear chain or branched; one or More groups, aryl or heteroaryl containing between 3 and 30 Ring C Atoms and optionally substituted with R; a Group alcarilo or aralquilo containing between 1 and 30 C ATOMS, taking the terms and definitions above mention aryl alkyl Adas; a Group alquiltioalquilo alkoxyalkyl esters,,Alquilsulfonilalquilo or alquilaminoalquilo containing between 1 and 30 C ATOMS, in a linear chain or branched; one or more Heterocyclic groups containing between 5 and 10 membered Ring; or a combination of one or More groups mentioned above, while these groups optionally. Tuidos with R, with one or More groups, cyano, Nitro, hydroxyl, carbonyl or carboxyl, amino,With one or more halogens or with one or more functions or Nitrile, aldehyde cyanohydrin and, where R and R 'together form a ring, this ring is as defined above, and, IF R represents h, then R' is different, and IF h, R 'is H, then R is different from H.
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