Use of benzo FUSED Heterocyclic sulfonamide derivatives for the treatment of mania and Bipolar Disorder

摘要

Method for Treatment of mania and / or bipolar disorder, which comprises administering to a Subject that needs a therapeutically effective amount of one or more Heterocyclic FUSED benzo sulfonamide Derivatives of formula (1) and (2) formula as defined here.Claim 1: a method to treat mania which comprises administering to a subject in need, a therapeutically effective amount of a compound of formula (1) wherein R1 and R2 are selected, each independentlyThe group consisting of H and Lower alkyl; R4 is selected from the group consisting of H and Lower alkyl; a is an integer from 1 to 2; The Ring R is selected from the group consisting of formulas (3) to (9) where B is an integer from 0 to 4; and where C is a number between RO from 0 to 2; each R5 independently selected from the group consisting HalogenLower alkyl, nitro; provided that if the Ring R is as in formula (8) or (9), then a is 1; or a Salt thereof acceptable from the standpoint of pharmacist.