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Pyrimidine derivatives and their use as inhibitors of fosfatidilnositol 3-kinase (PI3K)
Pyrimidine derivatives and their use as inhibitors of fosfatidilnositol 3-kinase (PI3K)
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机译:嘧啶衍生物及其作为磷酰肌醇3-激酶(PI3K)的抑制剂的用途
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摘要
A tienopirimidina formula (1), and their pharmaceutically acceptable salts are inhibitors of PI3K activity by the p110alpha subtype selectivity, and can be used to treat diseases and disorders that arise from the growth, function, or abnormal Cell behavior, including The Associated with PI3 kinase, such as cancer, immune disorders,Cardiovascular Diseases, Viral Infections, inflammation, Metabolic Disorders and Endocrine and neurological disorders. Also identify processes to synthesize compounds. Claim 1: a tienopirimidina is a compound of formula (1) or a pharmaceutically acceptable Salt thereof.
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