methods for solubilizing latanoprost and preparing an aqueous latanoprost ophthalmic solution and resulting solution

摘要

METHODS FOR SOLUBILIZING LATANOPROST AND PREPARING A WATER LATANOPROST Ophthalmic Solution AND RESULTING SOLUTION. The invention relates to a method for solubilizing a prostaglandin F2? Analogous active agent such as latanoprost, and a method for preparing an aqueous ophthalmic solution from solubilized latanoprost for the treatment of various eye disorders. The present invention furthermore relates to an aqueous ophthalmic solution resulting from said method, which is characterized by its chemical stability at room temperature, safety, safety and effectiveness in treating the patient. The new aqueous ophthalmic solution is distinguished because its pharmaceutical value lies in the management of an easily accessible vehicle that not only allows for the solubility of latanoprost, but also favors its chemical stability and increased patient tolerance for its treatment. suffering.