dosage unit form for buccal administration, use of the dosage unit form and method for preparing the dosage unit form

摘要

UNIT DOSAGE FORM FOR MUCKAL ADMINISTRATION, USE OF THE UNIT DOSAGE FORM AND METHOD FOR PREPARING THE UNIT DOSAGE FORM - The present invention provides a composition (eg a pharmaceutical composition) comprising at least one release agent compound and at least one peptide YY (PYY) is a PYY agonist. Preferably, the composition includes a therapeutically effective amount of peptide YY or PYY agonist and the release agent compound. The composition of the present invention facilitates the release of PYY, a PYY agonist, or a mixture thereof, and increases its bioavailability compared to administration without the release agent compound. PPY and PYY agonists have activity as agents to reduce nutrient availability, including reduced food intake.