compound, pharmaceutical composition. methods of inhibiting the binding of endogenous ligands to the crth-2 receptor in a cell, treating, ameliorating or preventing a disorder responsive to inhibiting the binding of endogenous ligands to the crth-2 receptor in an animal and preparing a compound, and kit

摘要

"COMPOSITION, PHARMACEUTICAL COMPOSITION, METHOD OF INHIBITING THE CONDUCTION OF ENDOGENAL LIGANDS TO THE CRTH-2 RECEIVER IN A CELL, TO TREAT, IMPROVE OR PREVENT A DISTURBANCE RESPONSIBLE TO THE RECYGEN AND ALLOUND LIGO 2 INJECTION A COMPOUND, AND, KIT ". The invention relates to benzimidazole acetic acid compounds which function as antagonists of the homologous T-helper T-receptor receptor (CRTH2) homologous receptor molecule. The invention also relates to the use of such compounds to inhibit the binding of protaglandin D2-2 and its metabolites or certain thromboxane metabolites to the CRTH2 receptor and to treat disorders in response to such inhibition.