Compounds with activity of u00econs channel of Kv4

摘要

Compounds with activity of Kv4 u00econs channel of the present invention refers to compounds that interact with ion channels.Particularly, the invention relates to compounds that have structural formula (I), (II), (III), or (IV), their stereoisomers, tautu00f3meros, racu00eamicos, pro drugs, metabolites, or a salt, and / or a pharmacologically acceptable solvato thereof, formula (I), (II), (III), (IV), in which X Xu00ac n n, N, y, Z, W, ru00ac n, ru00ac 8u00ac, ru00ac 9u00ac ru00ac 10u00ac, l, a, Z and n have the meanings defined in claim 1.The invention also relates to methods for the preparation of these compounds, to pharmaceutical compositions comprising these compounds, and the use of these compounds in methods for the treatment of the body of humans and animals.