首页> 外国专利> Substituted pyrimidines derived Compounds, Preparation Method, Pharmaceutical Composition and use for the treatment of inflammatory or obstructive Diseases of respiratory tractS, pulmonary hypertension, pulmonary fibrosis, FIBRO

Substituted pyrimidines derived Compounds, Preparation Method, Pharmaceutical Composition and use for the treatment of inflammatory or obstructive Diseases of respiratory tractS, pulmonary hypertension, pulmonary fibrosis, FIBRO

机译:取代的嘧啶类化合物,制备方法,药物组合物以及用于治疗呼吸道,肺动脉高压,肺纤维化,FIBRO的炎性或阻塞性疾病的用途

摘要

Compounds of formula (I) in free or salt or solvate form, where T1, T2, Ra and Rb have the meanings as indicated in the specification, are useful for treating inflammatory or obstructive airways, pulmonary hypertension, pulmonary fibrosis, liver fibrosis, muscle diseases and systemic skeletal disorders. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
机译:游离或盐或溶剂化物形式的式(I)化合物,其中T1,T2,Ra和Rb具有说明书中指示的含义,可用于治疗发炎或阻塞性气道,肺动脉高压,肺纤维化,肝纤维化,肌肉疾病和全身性骨骼疾病。还描述了包含所述化合物的药物组合物和制备所述化合物的方法。

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