首页> 外国专利> Spiro compounds derived from 3H (1 - benzofuran - 2,4 '- piperidine); Preparation Process; Intermediate Compounds, Pharmaceutical Composition and use for the treatment of respiratory diseasesSuch as COPD and Asthma.

Spiro compounds derived from 3H (1 - benzofuran - 2,4 '- piperidine); Preparation Process; Intermediate Compounds, Pharmaceutical Composition and use for the treatment of respiratory diseasesSuch as COPD and Asthma.

机译:衍生自3H的螺化合物(1-苯并呋喃-2,4'-哌啶);制备过程;中间体化合物,药物组合物以及用于治疗呼吸系统疾病(如COPD和哮喘)的药物。

摘要

Compounds of formula (I) wherein R1, R3, R4, R5, R6, R7, and R10 are as defined in the specification, are described. The present invention also relates to pharmaceutical composition comprising said compounds and to the use of said compounds in therapy. The present invention further relates to processes for the preparation of said compounds and to new intermediates useful in the preparation thereof. Beside, the invention relates to salts and polymorphic forms of the new compounds as well as the preparation thereof.
机译:描述了其中R 1,R 3,R 4,R 5,R 6,R 7和R 10如说明书中所定义的式(I)化合物。本发明还涉及包含所述化合物的药物组合物以及所述化合物在治疗中的用途。本发明进一步涉及所述化合物的制备方法和用于制备其的新中间体。另外,本发明涉及新化合物的盐和多晶型形式及其制备。

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