Release System comprising flibanserin Pharmaceutical excipient and at least one farmaceuticamentre acceptable; and its use for the treatment of central nervous system DisordersAffective Disorders, sleep and Sex, among others.

摘要

The present invention provides pharmaceutical release systems comprising an therapeutically effective amount of flibanserin and at least one pharmaceutically acceptable excipient, characterized in that said pharmaceutical release systems exhibit a pharmacokinetic profile that is characterized by an average maximum flibanserin plasma concentration Cmax lower than 300 ng/mL, preferably lower than 200 ng/mL after administration of a single dose to healthy volunteers in fasted state or directly after a meal.