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Solid pharmaceutical dosage form for oral administrationComprising an Amorphous or Crystalline form of a compound in a microincluido Ionic Polymer insoluble in water in proportion of 1: 5: 5; and the preparation method.
Solid pharmaceutical dosage form for oral administrationComprising an Amorphous or Crystalline form of a compound in a microincluido Ionic Polymer insoluble in water in proportion of 1: 5: 5; and the preparation method.
The present invention provides novel pharmaceutical solid dosage forms for oral administration comprising a therapeutically effective amount of an unstable crystalline form or an amorphous form of a therapeutically effective compound micro-embedded into an ionic water-insoluble polymer. The therapeutically effective compounds, which have a tendency to gel, are micro-embedded into an ionic water-insoluble polymer matrix to provide a dosage form having rapid, reproducible, and complete dissolution profiles. These novel solid pharmaceutical dosage forms are useful in the treatment or control of a number of diseases. The present invention also provides a method for treating a disease comprising administering to a subject, in need thereof, a therapeutically effective amount of the novel solid pharmaceutical dosage form. The present invention further provides a method for preparing the pharmaceutical dosage forms.
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