A fusion protein consisting of an immunoglobulin FC region with a fragment or a soluble domain of FGF receptor; polynucleotide that encodes and vector and cell that include; comPosition includes Fu Pharmaceutical Protein

摘要

The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules.