Use of Derivatives of urea compounds useful in the prophylaxis and Therapy of secondary prevention, one or more Disorders associated with thrombosis, embolism,Hypercoagulability or fibrotic changes; urea Compounds, Preparation method

摘要

The invention relates to compounds of the formula I as defined herein, which are inhibitors of activated thrombin-activatable fibrinolysis inhibitor. The compounds of the formula I are suitable for manufacturing medicaments for the prophylaxis, secondary prevention and therapy of one or more disorders which are associated with thromboses, embolisms, hypercoagulability or fibrotic changes.