- Spiro piperidine Compounds, vasopressin V1a receptor modulators; extraction process; Pharmaceutical Composition and use in the treatment of diseases such as dysmenorrhea,Hypertension, Anxiety and Depressive Disorders.

摘要

The present invention is concerned with novel spiro-piperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful in the prevention and/or treatment of anxiety and depressive disorders and other diseases. In particular, the present invention is concerned with compounds of the general formula (I) wherein R1 to R5, R5', X, Y and A are as defined in the specification.