Aprotinas non-native variants (hbikd2) because they show an expression Enhanced at least 2 Times compared with Native hbikd2; Nucleic Acid encoding; use this variant to treat HemOrragias.

摘要

The present invention relates to novel variants of domain 2 of the human placental bikunin with improved expression levels and favorable serine protease-inhibitory properties and their production and use.