the group of inventions relates to the allocation of biologically active substances from hypothyroid animals and for the drug form for the sake u043fu0430u0440u0435u043du0442u0435u0440u0430u043bu044cu043du043eu0433u043e the sight.which can be used in medicine as a means of u043du043eu0440u043cu0430u043bu0438u0437u0443u044eu0449u0435u0435 thyroid function.a u043du043eu0440u043cu0430u043bu0438u0437u0443u044eu0449u0435u0435 function of thyroidimplemented in the form of a drug form for u043fu0430u0440u0435u043du0442u0435u0440u0430u043bu044cu043du043eu0433u043e introduction and represents the u043fu0435u043fu0442u0438u0434u043du044bu0439 complex containing u043du0438u0437u043au043eu043cu043eu043bu0435u043au0443u043bu044fu0440u043du043eu0439 fractions from 70 to 90%.with the molecular mass of the peptide components in the range from 74 to the right, with the concentration of polypeptides 2.5 - 29 mg / ml and obtained from the thyroid gland calves not older than 12 months of age or pigs by extraction of acetic acid in the presence of zinc chloride.a means of obtaining funds, u043du043eu0440u043cu0430u043bu0438u0437u0443u044eu0449u0435u0433u043e thyroid function, characterized by the factwhat thyroid calves not older than 12 months of age or swine, frozen at a temperature of not less than minus m, and at a temperature of minus 20 22u00b0u0441 in t u0435u0447u0435u043du0438u0435 not less than two months.then are added 3% solution of acetic acid in the ratio of 1: 5 at a temperature 20u00b15u00b0u0441, extractions are under constant u043fu0435u0440u0435u043cu0435u0448u0438u0432u0430u043du0438u0438,after obtaining the homogeneous suspensions are added to a 1% solution of zinc chloride in the ratio of 50: 1, cooled at constant temperature u043fu0435u0440u0435u043cu0435u0448u0438u0432u0430u043du0438u0438 to 7 - 16 oc.then mix for 1 h every 4 h advance within 48 h, extract is separated from the ballast substances u0441u0435u043fu0430u0440u0438u0440u043eu0432u0430u043du0438u0435u043c, u044du043au0441u0442u0440u0430u043au0442u0443 add acetone for m the ratio of 1: 5and at 3 - 5 * for 4 h, the u0433u043eu043cu043eu0433u0435u043du0438u0437u0438u0440u043eu0432u0430u043du043du044bu0439 residue repeatedly besieged by acetone at least 2 times, then the residue.
展开▼