N-ACYL DERIVATIVES OF AMINO ACIDS, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITION AND APPLICATION AS ANTIALLERGY, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS

摘要

The present invention relates to N-acyl derivatives of amino acids of the general formula (I) wherein n is 2 or 3; and R are their pharmaceutically acceptable salts, to new methods for their preparation, their use as anti-allergic, anti-anaphylactic, anti-inflammatory and lipid-lowering agents, as well as to a pharmaceutical composition containing these compounds in an effective amount and a method for treating allergic and inflammatory diseases and lipid metabolism disorders: bronchial asthma, allergic rhinitis, pollinosis, seasonal and year-round rhinitis, allergic pneumonia, atonic rmatita, psoriasis, urticaria, allergic (including anaphylactic) reactions to insect stings and medicaments, cold allergy, allergic conjunctivitis, atherosclerosis, obesity, ischemic heart and brain disease, myocardial infarction, stroke.