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CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEUROPATHIC PAIN AND CLUSTER AND MIGRAINE HEADACHE-ASSOCIATED PAIN
CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEUROPATHIC PAIN AND CLUSTER AND MIGRAINE HEADACHE-ASSOCIATED PAIN
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机译:氨基甲酸酯化合物,用于预防或治疗神经病性疼痛以及与头痛和偏头痛的头痛相关联的疼痛
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摘要
This invention is directed to a method for preventing or treating neuropathic pain and cluster and migraine headache-associated pain comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of Formula (I) substantially free of other enantiomers or an enantiomeric mixture wherein an enantiomer of Formula (I) predominates: wherein phenyl is substituted at X with one to five halogen atoms independently selected from the group consisting of fluorine, chlorine, bromine and iodine; and; RSUB1 /SUBand RSUB2 /SUBare independently selected from the group consisting of hydrogen and CSUB1/SUB-CSUB4 /SUBalkyl; wherein CSUB1/SUB-CSUB4 /SUBalkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of hydrogen, halogen, CSUB1/SUB-CSUB4 /SUBalkyl, CSUB1/SUB-CSUB4 /SUBalkoxy, amino, nitro and cyano).
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