MEDICINAL APPLICATIONS OF COMPOUNDS SYNTHESIZED ON THE BASIS OF STEROIDAL SAPOGENIN-TIGOGENIN FROM THE PLANT YUCCA GLORIOSA CULTIVATED IN GEORGIA

摘要

Steroidal derivatives of immense potential as drug molecules have been prepared on the basis tigogenin-sapogenin from the plant Yucca gloriosa cultivated in Georgia Preparation methods to get Bis-m-bromobenzoic acid hydrazone of 5 a-androstane-3, 17-dione and Bis-m-nitrobenzoic acid hydrazone of 5 a-androstane-3, 17-dione are given. The steroids Bis-m-bromobenzoic acid hydrazone of 5 a-androstane-3, 17-dione and Bis-m-nitrobenzoic acid hydrazone of 5 a-androstane-3, 17-dione have shown promising anti TB, anticancer and anti HIV activities in vitro.