A METHOD OF IDENTIFYING A COMPOUND THAT AMELIORATES PRE-ECLAMPSIA OR ECLAMPSIA AND THE IDENTIFIED COMPOUND

摘要

The present invention relates to a method of identifying a compound that ameliorates pre-eclampsia or eclampsia, said method comprising contacting a cell that , expresses a sF It-I, VEGF, or PIGF nucleic acid molecule with a candidate compound, and comparing the level of expression of said nucleic acid molecule in said cell contacted by said candidate compound with the level of expression in a control cell not contacted by said candidate compound, wherein an alteration in expression of said sFlt:-l, VEGF, or PIGF nucleic acid molecule identifies said candidate compound as a compound that ameliorates pre-eclampsia or eclampsia.