Use of hydroxylamine derivatives for preparing a medicament for treating and prevention of diseases connected with dysfunction of vascular endothelial cells and pharmaceutical composition containing thereof

摘要

PCT No. PCT/HU97/00044 Sec. 371 Date Dec. 6, 1999 Sec. 102(e) Date Dec. 6, 1999 PCT Filed Aug. 6, 1997 PCT Pub. No. WO98/06400 PCT Pub. Date Feb. 19, 1998The invention relates to a method of treating or preventing illnesses resulting from damaged endothelial cells, wherein the method comprises administering to a patient a product comprising hydroxylamine derivatives of the general formulae (I) with the proviso that in the compounds of general formula (I) when X comprises a -NR3R4 group and Y comprises a hydroxyl group, the X group is condensed with the Y substituent to form an intramolecular ring represented by general formula (Ill)