Pharmaceutical composition containing zofenopril / HCTZ for the treatment of hypertension

摘要

For a Solid oral Pharmaceutical composition containing zofenopril or a Salt thereof in an amount greater than 10% of the total weight of the composition, hydrochlorothiazide (HCTZ) in an amount of more than 4% by weight of the total Composition and excipients, where z is the preferred calcium salt Ofenopril polymorphic to pure Polymorph B.It also relates to a preparation method of the oral dosage form. Said composition is useful in the treatment of hypertension