Tetrahydrofluorocarbon derivatives and their preparation procedures

摘要

It refers to tetrahydrofluorocarbons (IA), wherein R1 and R2 are h, hydroxy, halogenated and perfluoroalkyl (C1-C5), respectively,Bitumen (C1-C5),Among other things, R3 is a substitute for H, hydroxy, halogenated, CN, tar (C1-C10), which is replaced by Oh, CN, nitro, halogenated, etc.; R4 is an optional tar (C1-C10), which is replaced by 1-3 hydroxy, halogenated or oxygen (C1-C5),Bicycle (C3-C7),Arilo（C6-C14），R5 is, among other things, fluorinated tar (C1-C10), cyclomequine (C3-C7),1. Asphalt (C1-C8) cyclopropyl (C3-C7);Among other things, isocyclohexane; R6 is methyl, ethyl, propyl, isopropyl, or ethylene. 6, 7, 7, 7, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, 6, (E) 5 - (7) -2-fluoro-8-methyl-6 - (trifluoromethyl) - 5,6,7,8-tetrahydrofluoroethane-1,6-diol;There are others He also mentioned a drug synthesis and a preparation procedure. These compounds inhibit the secretion of IL-8 cytotoxin and can be used to treat COPD, bronchitis, rheumatism and psychosis.