AMORPHOUS RAPAMYCIN 42-ESTER WITH 3-HYDROXY-2- (HYDROXYMETHYL)-2-METHYLPROPIONIC ACID AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

摘要

47 ABSTRACTAMORPHOUS RAPAMYCIN 42-ESTER WITH 3-HYDROXY-2-(HYDROXYMETHYL)-2-METHYLPROPIONIC ACID AND 9-&PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAMEThe present invention provides an amorphous form of rapamycin 42-ester with 3-hydroxy-2-(hydroxymethyl)-2-methyl prop ionic acid. This invention also provides processes for preparing the amorphous form and pharmaceutical compositions including the amorphous form.FIG. 1A-D~~~~