Molecular orientation of macromolecules by the action of a meniscus on highly specific surfaces.

摘要

The invention refers to a surface GREATLY SPECIFIC TO BIOLOGICAL REACTIONS. The surface comprises a support having at least one layer of a compound organic. THIS IS ORGANIC COMPOUND OUT OF THE CAPA, an exposed group having an affinity for one serving, INCLUDING ONE END of a biologically active molecule. OTHER ELEMENTS OF THE LAYER have essentially no activity for molecules biologically active REACTION CONDITIONS DADAS. PREFERABLY EXPOSED GROUP IS COUPLED TO SUPPORT THROUGH A GROUP OF FIXING. SURFACE and substrate can be included in STRUCTURES AND DEVICES SUITABLE FOR MEASUREMENTS optical, fluorescence, chemiluminescence, PROBES EXPLORATION AND / OR ELECTRIC. The invention also relates to a process for stretching macromolecules the surface (S) of a support. This process means, moves a meniscus showing a triple bottom line (S / A / B) ON THE SURFACE OF CONTACT YRESULTA of a solvent (A) with the surface (S) and means (B). PREFERABLY SHIFTING meniscal done well Evaporative OR BY MAKING USE OF MECHANICAL SHEAR MOVEMENT OF TWO SUPPORTS, relative to each other.