XAG PROTEIN IN THE IN VITRO DIAGNOSIS OF PANCREATIC DUCTAL ADENOCARCINOMA

摘要

The present invention refers to an in vitro method to detect pancreatic ductal adenocarcinoma in an individual, to determine the stage or severity of said condition in an individual, or to monitor the effect of therapy administered to an individual with either one or both of said condition to screen for, identify, develop and evaluate the efficacy of compounds for the treatment of said condition of the pancreas aimed at developing new medicinal products, as well as agents that inhibit the expression and/or activity of the XAG protein (anterior gradient 2 homolog-Xenopus laevis-aliases: AGR2, AG2, GOB-4, HAG-2, XAG-2. UniGene: Hs.226391, GeneBank: NM_006408) and/or the effects of said expression.