Microporous membrane substrate with caustic solutions resistant surface with low affinity for proteins.

摘要

A porous, clean, resistant to caustic solutions comprising a microporous membrane substrate and a thermosetting surface biomolecule resistant formed separately and having a binding capacity of less than 30 micrograms per square centimeter biomolecules, as membrane binding assay of IgG, wherein said heat stable biomolecule resistant surface is a surface coating formed separately comprising: a first coating comprising a first crosslinked terpolymer, said comprising terpolymer at least two monofunctional monomers selected from the group It is consisting of acrylamides, methacrylamides and N-vinyl pyrrolidones, and at least one polyfunctional monomer selected from the group consisting of polyfunctional acrylamides, polyfunctional methacrylamides and diacroylpiperazines and a second coating comprising a second crosslinked terpolymer or copolymer modified with groups functional selected from the group consisting of hydrophilic functional groups and hydrophobic functional groups.