首页> 外国专利> PLANT-OPTIMIZED GENES ENCODING PESTICIDAL TOXINS

PLANT-OPTIMIZED GENES ENCODING PESTICIDAL TOXINS

机译:植物优化基因编码农药

摘要

The subject invention concerns materials and methods useful in the control ofpests and, particularly, plant pests. More specifically, thesubject invention provides plant-optimized, polynucleotide sequences thatencode pesticidal toxins (full-length and truncated). Truncatedpolynucleotide sequences can be used to produce truncated toxins or for theproduction of fusion (or chimeric) genes and proteins.The polynucleotide sequences of the subject invention have certainmodifications, compared to wild-type sequences, that make themparticularly well-suited for optimized expression in plants. Using techniquesknown to those skilled in the art, the polynucleotide sequencesdescribed herein can be used to transfer plants in order to confer pestresistance upon said plants. The subject invention further providesplant-optimized, polynucleotide sequences that encode C-terminal, protoxinportions that can be used with genes encoding truncated, coretoxins to produce full-length toxins. In addition, the subject inventionprovides preferred amino acid sequences that are encoded by theplant-optimized polynucleotide sequences disclosed herein.
机译:本发明涉及可用于控制糖尿病的材料和方法。害虫,尤其是植物害虫。更具体地说,本发明提供了植物优化的多核苷酸序列,其编码农药毒素(全长和截短)。截断多核苷酸序列可用于产生截短的毒素或用于融合(或嵌合)基因和蛋白质的产生。本发明的多核苷酸序列具有某些与野生型序列相比,使它们特别适合在植物中优化表达。使用技巧本领域技术人员已知,多核苷酸序列本文所述可用于转移植物以赋予害虫对所述植物的抗性。本发明进一步提供植物优化的编码C末端毒素的多核苷酸序列可以与编码截短,核心的基因一起使用的部分毒素产生全长毒素。另外,本发明提供优选的氨基酸序列,由本文公开的植物优化的多核苷酸序列。

著录项

  • 公开/公告号CA2309131C

    专利类型

  • 公开/公告日2008-01-15

    原文格式PDF

  • 申请/专利权人 MYCOGEN CORPORATION;

    申请/专利号CA19982309131

  • 申请日1998-11-04

  • 分类号C12N15/32;A01N63/50;A01N63/60;A01P7/04;C12N5/10;C12N15/62;

  • 国家 CA

  • 入库时间 2022-08-21 20:04:04

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