HISTOPHILUS SOMNI ANTIGENS, COMPOSITIONS AND METHODS OF USE

摘要

This invention provides, among other things, protein, polypeptides, andfragments thereof, derived from bacteriaHistophilus somni. Also provided are nucleic acids encoding for such proteins,polypeptides, and/or fragments, as well as nucleicacids complementary thereto. Additionally, this invention provides antibodieswhich bind to the proteins, polypeptides, and/orfrag-ments. This invention further provides expression vectors useful formaking the proteins, polypeptides, fragments, and/or nucleicacids, for use as vaccines, diagnostic reagents, immunogenic compositions, andthe like. Methods of making the compositionsand methods of treatment with the compositions are also provided. Thisinvention also provides methods of detecting the proteins,polypeptides, fragments, variants and/or nucleic acids as well as detectingantibodies against the proteins, polypeptides, variants andfragments.