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MOLECULAR INTERACTION SITES OF 16S RIBOSOMAL RNA AND METHODS OF MODULATING THE SAME
MOLECULAR INTERACTION SITES OF 16S RIBOSOMAL RNA AND METHODS OF MODULATING THE SAME
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机译:16S核糖体RNA的分子相互作用位点及其调控方法
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摘要
Polynucleotides comprising molecular interaction sites of 16S rRNA that have particular secondary structure are provided. Methods of using such polynucleotides to screen, virtually or actually, combinatorial libraries of compounds that bind thereto are also provided. Method of modulating the activity of 16S rRNA by contacting 16S rRNA or prokaryotic cells containing the same with a compound identified by such virtual or actual screening are also provided.
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