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METHODS FOR LOWERING HIF-1 MEDIATED GENE EXPRESSION
METHODS FOR LOWERING HIF-1 MEDIATED GENE EXPRESSION
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机译:减少HIF-1介导的基因表达的方法
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摘要
The present invention relates to the elucidation of specific molecular features of endogenous amino acids and their derivatives for inhibiting hypoxia-inducible gene expression by preventing inactivation of hypoxia-inducible factor hydroxylating enzymes. This invention encompasses agents that can be used to reduce tissue vascularization, cancer cell survival, and to treat obesity.
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