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INTRAOCULAR LENS WITH DRUG DELIVERY SYSTEM ATTACHED THERETO

机译:附有带药物输送系统的眼内透镜

摘要

The present invention relates to a device comprising an intraocular lens and a drug delivery system attached thereto, wherein said drug delivery system is or can be loaded with one or more therapeutic agents. Preferably, said drug delivery system comprises a biodegradable matrix material wherein said biodegradable matrix material is preferably selected from the group consisting of: poly(lactic acid), poly(glycolic acid), poly(lactide-co-glycolide), polycaprolactones, polyorthoesters, polyanhydrides, polyesteramides and mixtures thereof. Preferred therapeutic agent(s) is/are selected from anti-inflammatory agents, anti-vasoproliferative agents, immunosuppressive agents, antibiotics, antiviral agents, anti-mitotic agents and combinations thereof. Also provided is a method of treatment and/or prevention of one or more diseases or malfunctions of the eye, comprising implanting one, two, three or more devices of the invention into an eye of a patient.
机译:本发明涉及一种包括眼内透镜和附接到其上的药物输送系统的装置,其中所述药物输送系统装载有或可以装载一种或多种治疗剂。优选地,所述药物递送系统包括可生物降解的基质材料,其中所述可生物降解的基质材料优选选自:聚乳酸,聚乙醇酸,聚丙交酯-乙交酯,聚己内酯,聚原酸酯,聚酸酐,聚酯酰胺及其混合物。优选的治疗剂选自抗炎剂,抗血管增生剂,免疫抑制剂,抗生素,抗病毒剂,抗有丝分裂剂及其组合。还提供了一种治疗和/或预防眼睛的一种或多种疾病或功能失调的方法,包括将本发明的一个,两个,三个或更多个装置植入患者的眼睛。

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