首页> 外国专利> METHOD FOR THE PREPARATION OF A BIOCOMPATIBLE GEL WITH CONTROLLED RELEASE OF ONE OR MORE ACTIVE INGREDIENTS WITH LOW SOLUBILITY IN WATER, GELS THUS OBTAINED AND THEIR USE

METHOD FOR THE PREPARATION OF A BIOCOMPATIBLE GEL WITH CONTROLLED RELEASE OF ONE OR MORE ACTIVE INGREDIENTS WITH LOW SOLUBILITY IN WATER, GELS THUS OBTAINED AND THEIR USE

机译:一种可控制释放一种或多种在水中溶解度低的活性成分的生物相容性凝胶的制备方法及其用途

摘要

This invention concerns a process for the preparation of a biocompatible gel with controlled release of one or more active lipophilic and/or amphiphilic ingredients comprising a matrix based on one or several biopolymers with or without a functional group, in which in a first step, the lipophilic and/or amphiphilic active ingredient(s) are mixed in a homogenous manner, by dissolution in biocompatible alcohol or a mixture of biocompatible alcohols; in a second step, the homogenous mixture obtained in the first step is mixed with a biocompatible gel comprising a matrix made of one or several biopolymers with or without a functional group. Also described are gels obtained by the method of the present invention and their use in cosmetic and therapeutic fields.
机译:本发明涉及一种制备生物相容性凝胶的方法,该生物相容性凝胶具有一种或多种活性亲脂性和/或两亲性成分的控制释放,所述成分包含基于具有或不具有官能团的一种或几种生物聚合物的基质,其中在第一步中,通过溶解在生物相容性醇或生物相容性醇的混合物中,以均质方式混合亲脂和/或两亲活性成分。在第二步骤中,将在第一步骤中获得的均质混合物与生物相容性凝胶混合,该凝胶包括由一种或多种具有或不具有官能团的生物聚合物制成的基质。还描述了通过本发明的方法获得的凝胶及其在美容和治疗领域中的用途。

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