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X-RAY CONTRAST AGENT USING GOLD NANOPARTICLES AND PROCESS FOR PREPARING THE SAME

机译:使用金纳米粒子的X射线造影剂及其制备方法

摘要

Provided are an X-ray contrast agent using gold nanoparticles and a process for preparing the X-ray contrast agent. The X-ray contrast agent is prepared by capping gold nanoparticles with polyethylene glycol (PEG). The X-ray contrast agent is nontoxic and remains in a blood vessel for a long time so that the X-ray contrast agent can be usefully used as a computed tomography (CT) contrast agent for imaging blood vessels. Therefore, the X-ray contrast agent is useful for inspecting blood vessel structures and new blood vessels in a tumor, and obtaining perfusion images. In addition, gold provides better visibility than iodine when used in an X-ray contrast agent. Therefore, better x-ray images can be obtained using the X-ray contrast agent containing gold nanoparticles.
机译:提供了一种使用金纳米颗粒的X射线造影剂以及制备该X射线造影剂的方法。 X射线造影剂是通过用聚乙二醇(PEG)覆盖金纳米颗粒来制备的。 X射线造影剂是无毒的,并且在血管中保留了很长时间,因此X射线造影剂可以有效地用作计算机断层摄影(CT)造影剂以使血管成像。因此,X射线造影剂可用于检查肿瘤中的血管结构和新血管并获得灌注图像。此外,与X射线造影剂相比,金的可见度比碘更好。因此,使用包含金纳米颗粒的X射线造影剂可以获得更好的X射线图像。

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