GENETIC RISK FACTOR IN SOD1 AND SFRS15 IN RENAL DISEASE, DIABETIC CATARACT, CARDIOVASCULAR DISEASE AND LONGEVITY

摘要

The invention relates to a composition comprising an isolated nucleic acid sequence that specifically hybridizes to at least one of SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5, SEQ ID NO:7, SEQ ID NO:9 and their complements. The composition is useful as a probe to detect the presence of at least one allele of three single nucleotide polymorphisms (SNPs) that are associated with renal disease, cataract, cardiovascular disease and longevity.