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) T E TEXT AS EEN ESTA S E Y T S UT O TY TO REA AS O OWS: 1- (4- BENZOYL (METHYL) AMINO -3- (PHENYL) BUTYL AZETIDINE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS 3
) T E TEXT AS EEN ESTA S E Y T S UT O TY TO REA AS O OWS: 1- (4- BENZOYL (METHYL) AMINO -3- (PHENYL) BUTYL AZETIDINE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS 3
The present invention relates to novel 1- [ (4- [3-chloro-5- (trifluoromethyl) benzoyl (methyl) amino] -3- (4- fluorophenyl) butyl] -3-morpholin-4-yl-azetidine derivatives, as well as salts and enantiomers thereof. The invention also relates to pharmaceutical compositions comprising said compounds, and to the use of said compounds in therapy, e.g. in the treatment of gastrointestinal disorders. The invention further relates to processes for the preparation of the compounds. The compounds are neurokinin (NK) receptor antagonists.
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