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VACCINE FOR TRANSCUTANEOUS IMMUNIZATION AGAINST TRAVELLERS' DIARRHOEA
VACCINE FOR TRANSCUTANEOUS IMMUNIZATION AGAINST TRAVELLERS' DIARRHOEA
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机译:防止伤寒者进行即时免疫接种的疫苗
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摘要
A vaccine delivered by transcutaneous immunization provides an effective treatment against infections by pathogens such as, for example, enterotoxigenic Escherichia coli (ETEC) and/or for symptoms of diarrheal disease caused thereby. For example, one, two, three, four, five or more antigens derived from ETEC and capable of inducing an antigen-specific immune response (e.g., toxins, colonization or virulence factors) and one or more optional adjuvant (e.g., whole bacterial ADP-ribosylating exotoxins, B subunits or toxoids thereof, detoxified mutants and derivatives thereof) are used to manufacture vaccines or to induce systemic and/or mucosal immunity.
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