首页> 外国专利> METHOD FOR SELECTIVELY FUNCTIONALIZING NON-MODIFIED SOLID SURFACE AND METHOD FOR IMMOBILIZING ACTIVE MATERIAL ON THE FUNCTIONALIZED SOLID SURFACE

METHOD FOR SELECTIVELY FUNCTIONALIZING NON-MODIFIED SOLID SURFACE AND METHOD FOR IMMOBILIZING ACTIVE MATERIAL ON THE FUNCTIONALIZED SOLID SURFACE

机译:选择性功能化非改性固体表面的方法和将活性物质固定在功能化固体表面上的方法

摘要

Provided is a method for selectively functionalizing unmodified solid surface, not oxidized and nitrified, into an aldehyde group, and a method for immobilizing an active material such as bio material or functional material on the functionalized aldehyde solid surface through strong and stable chemical bonding. Differently from a conventional method immobilizing deoxyribonucleic acid (DNA) using a cross linker, the method of the present invention does not require a cross linker reaction step to thereby shorten a process. Also, since a cross linker is absent, the monomolecular layer on the surface of a device i s thin, which reduces a perturbation effect by molecular layer. This is useful in fabrication of molecular electronic devices and bio- active devices. In addition, since the bio material or functional material is selectively immobilized only on the unmodified surface, the present invention can functionalize only a specific solid surface and develop a highly sensitive sensor and an improved functional device.
机译:提供了一种将未氧化和硝化的未改性固体表面选择性地官能化为醛基的方法,以及通过牢固且稳定的化学键合将生物材料或功能材料等活性物质固定在官能化醛固体表面上的方法。与使用交联剂固定脱氧核糖核酸(DNA)的常规方法不同,本发明的方法不需要交联剂反应步骤从而缩短了工艺。另外,由于不存在交联剂,所以器件表面上的单分子层很薄,这降低了分子层的干扰作用。这在分子电子设备和生物活性设备的制造中很有用。另外,由于生物材料或功能材料仅选择性地固定在未改性的表面上,因此本发明可以仅使特定的固体表面功能化,并开发出高度灵敏的传感器和改进的功能装置。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号