METHODS AND USES OF THE INTEGRIN ALPHA 10 CHAIN, FOR DIAGNOSING AND DETECTING ATHEROSCLEROSIS PLAQUE FORMATION IN VITRO

摘要

An antigen indicative of the presence of atherosclerotic plaque is provided. The antigen is used in a method for slowing or arresting progression and/or effecting regression of atherosclerotic plaque in a mammal, comprising administering to the mammal a binding agent having binding sites specific for said antigen of said mammal. Also included are methods for diagnosing a mammal who has a risk of developing atherosclerosis, comprising determining the amount of said antigen. Moreover, uses of said antigen for detection and diagnosing atherosclerosis is provided.