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Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors

机译:使用β-sheet模拟物作为蛋白酶和激酶抑制剂以及转录因子抑制剂

摘要

β-sheet mimetics and methods relating to the same are disclosed. The β-sheet mimetics have utility as protease and kinase inhibitors, as well as inhibitors of transcription factors. Methods of the invention include administration of a β-sheet mimetic, or use of the same for the manufacture of a medicament for treatment of a variety of conditions associated with the targeted protease, kinase and/or transcription factor.
机译:公开了β-折叠模拟物及其相关方法。 β-折叠模拟物可用作蛋白酶和激酶抑制剂以及转录因子抑制剂。本发明的方法包括给予β-折叠模拟物,或将其用于制备药物以治疗与靶标蛋白酶,激酶和/或转录因子相关的多种病症。

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