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COMBINATION MEDICATION FOR TREATING THE EFFECTS OF STOMACH ACID REDUCTION MEDICATION ON BONE INTEGRITY

机译:联合用药治疗胃酸减少药对骨完整性的影响

摘要

A composition for addressing a calcium deficiency caused by chronic administration of proton pump inhibitors and other acid lowering agents comprised of at least one proton pump inhibitor and vitamin D. The composition can further include one or more of the following: at least one buffering agent in an amount sufficient to increase gastric fluid pH to a pH that prevents acid degradation of at least a portion of the proton pump inhibitor in the gastric fluid, a therapeutically effective amount of at least one non-steroidal anti-inflammatory drug, a therapeutically effective amount of at least one bisphosphonate or selective estrogen receptor modulator, and at least one calcium supplement.
机译:一种用于解决由长期施用质子泵抑制剂和其他降酸剂引起的钙缺乏症的组合物,该组合物包含至少一种质子泵抑制剂和维生素D。该组合物还可包含以下一种或多种:至少一种缓冲剂。足以将胃液pH升高至可防止胃液中至少一部分质子泵抑制剂酸降解的pH的量,治疗有效量的至少一种非甾体抗炎药,治疗有效量至少一种双膦酸盐或选择性雌激素受体调节剂,以及至少一种钙补充剂。

著录项

  • 公开/公告号WO2008085728A2

    专利类型

  • 公开/公告日2008-07-17

    原文格式PDF

  • 申请/专利权人 SUNDHARADAS RENJIT;

    申请/专利号WO2007US88824

  • 发明设计人 SUNDHARADAS RENJIT;

    申请日2007-12-26

  • 分类号A61K38/00;A61K31/355;

  • 国家 WO

  • 入库时间 2022-08-21 19:58:10

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