1-(SUBSTITUTED PHENYL)-5- METHYL- 2 - (1H) PYRIDONE IN THE MANUFACTURE OF MEDICAMENTS FOR TREATING FIBROSIS IN ORGANS OR TISSUES

摘要

The use of 1-(substituted phenyl)-5-methyl-2-(1H) pyridone in the manufacture of medicaments for treating fibrosis in organs or tissues. It indicates that 1-(substituted phenyl)-5-methyl-2-(1H) pyridone can inhibit the cells produced by various ECM, and their effect is higher than pirfenidone. Therefore, this tpye of compounds can be used as active ingredient for preparing the antifibrotic agent in organs and tissues.