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LOW-CALCEMIC 16,23-DIENE 25-OXIME ANALOGS OF 1alpha,25-DIHYDROXY VITAMIN D3
LOW-CALCEMIC 16,23-DIENE 25-OXIME ANALOGS OF 1alpha,25-DIHYDROXY VITAMIN D3
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机译:1α,25-二羟基维生素D3的低钙16,23-二烯25-氧类似物
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摘要
The present invention provides novel 16,23-diene 25-oxime ether analogs of 1,25-dihydroxy vitamin D3, compositions comprising these compounds and methods of using these compounds as inhibitors of CYP24. In particular, the novel compound of the invention are useful for treating diseases which benefit from a modulation of the levels of 1,25-dihydroxy vitamin D3, for example, cell-proliferative disorders.
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