METHOD OF TREATING ACID-SENSING ION CHANNEL MEDIATED PAIN, COUGH, AND CENTRAL NERVOUS SYSTEM DISORDERS

摘要

The present invention provides a variety of methods of treatment of acid-sensing ion channel (ASIC) mediated pain, cough, and central nervous system disorders by ASICs inhibition with a series of pyrazinoylguanidine compounds represented by formula (I) as defined herein.