SMALL-MOLECULE HEPATITIS C VIRUS (HCV) NS3/4A SERINE PROTEASE INHIBITORS

摘要

Compounds of Formula 5 and prodrug compounds of Formula 5 wherein G1 is H or OH; G2 is H, R', or CO2R'; G3, G4 and G5, are each independently selected from the group consisting of: H, R', OH, OR', F, Cl, Br, I, NH2, NHR', NR'2, CN, SH, SR', SO3H, SO3R', SO2R', OSO3R', and NO2; and R' is a one to four carbon alkyl group are provided. Uses of these compounds and methods of medical treatment involving these compounds for the treatment of hepatitis C are also provided.