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Gene expression associated with osteoblast differentiation

机译:与成骨细胞分化相关的基因表达

摘要

The present invention identifies genes whose expression pattern is altered when pre-osteoblastic cells undergo differentiation into mature osteoblasts. The genes identified may be used as markers for the differentiation process. The present invention also provides methods to screen agents that are capable of modulating the differentiation process. The present invention also provides methods of identifying therapeutic agents that stimulate bone formation by analyzing the expression of one or more of the genes identified.
机译:本发明鉴定了当成骨细胞前细胞经历分化成成熟成骨细胞时其表达模式改变的基因。鉴定出的基因可用作分化过程的标记。本发明还提供了筛选能够调节分化过程的试剂的方法。本发明还提供了通过分析一种或多种鉴定出的基因的表达来鉴定刺激骨形成的治疗剂的方法。

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